Advanced Progress in the Synthesis of 3-Picoline

Abstract

Pyridine bases, including pyridine and picolines (e.g., 2-picoline, 3-picoline and 4-picoline), are typical N-heterocyclic compounds, which are applied widely in various fields such as vitamin B and pesticide, particularly 3-picoline. In this paper, the current synthesis processes of 3-picoline are reviewed, the related advantages and disadvantages from these pathways are analyzed. The reasons for the deactivation of catalysts are explained and the new regeneration process is introduced. It is concluded that glycerol/ammonia is an ideal pathway for the synthesis of 3-picoline, as it possesses many advantages, e.g., enviroment friendly, safety, sustainable and low cost, which will become the growing trend in the future work. The development of a high-performance catalyst is highly desirable.

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	Luo Caiwu
	Jiang Fuliang
	Li Xiangyang
	Zhang Jun
	Chao Zisheng

Keywords： pyridine； 3-picoline； glycerol； ZSM-5； catalyst

Received 2016-12-08;

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Luo Caiwu, Jiang Fuliang, Li Xiangyang, Zhang Jun, Chao Zisheng.Advanced Progress in the Synthesis of 3-Picoline[J] Chemcial Industry and Engineering, 2018,V35(4): 24-31

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