二苯甲酮结晶热力学性质及其模型研究

摘要采用静态法测定了常压下在278.15~313.15 K温度范围内二苯甲酮在不同配比的甲醇-乙腈混合溶剂中的溶解度数据。实验结果表明，当溶剂组成固定时，二苯甲酮的溶解度随温度的升高而增大；同时，二苯甲酮在甲醇-乙腈混合溶剂中存在潜溶现象。此外，分别使用改进的Apelblat方程和λh方程拟合二苯甲酮的溶解度实验数据，结果表明2种模型均能取得较好拟合效果。最后，基于NRTL模型和实验获得的溶解度数据，计算并分析了二苯甲酮的混合和溶解过程的热力学性质。二苯甲酮溶解度的测定与关联能够为其结晶工艺的开发提供重要的理论依据。

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	房彬彬
	侯宝红
	黄欣
	王静康
	鲍颖
	郝红勋

关键词：二苯甲酮；溶解度；潜溶；混合和溶解热力学性质

Abstract： Solubility data of benzophenone in different proportions of methanol-acetonitrile mixtures was measured from 278.15~313.15 K by using a gravimetric method under atmospheric pressure. It was found that the solubility of benzophenone increased monotonically with increasing temperature when the solvent proportion was fixed. While, the cosolvency phenomenon could be observed. Furthermore, the experimental solubility data of benzophenone was fitted using the modified Apelblat equation and λh equation successfully. Finally, the mixing and dissolution thermodynamic properties of benzophenone were calculated and analyzed based on the NRTL model and the experimental solubility data. The solubility data and correlations obtained in this study provide a crucial theoretical basis for crystallization process design and optimize.

Keywords： benzophenone； solubility； cosolvency； mixing and dissolution thermodynamic properties

Received 2019-07-03;

Fund:科技部国家重点研发计划项目资助（2016YFB0600504）。

Corresponding Authors: 黄欣,E-mail:x_huang@tju.edu.cn;郝红勋,E-mail:hongxunhao@tju.edu.cn。 Email: x_huang@tju.edu.cn;hongxunhao@tju.edu.cn

About author: 房彬彬(1992-),男,硕士研究生,现从事工业结晶方面研究。

引用本文:

房彬彬, 侯宝红, 黄欣, 王静康, 鲍颖, 郝红勋.二苯甲酮结晶热力学性质及其模型研究[J]. 化学工业与工程, 2019,36(6): 1-8

Fang Binbin, Hou Baohong, Huang Xin, Wang Jingkang, Bao Ying, Hao Hongxun.Research on Thermodynamic Properties and Model of Benzophenone[J]. Chemcial Industry and Engineering, 2019,36(6): 1-8

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