Synthesis of pentaerythritol in microchannel reactor

化学工业与工程

Chemcial Industry and Engineering

2023, Vol. 40

Issue (6) :70-77 DOI: 10.13353/j.issn.1004.9533.20220310

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Synthesis of pentaerythritol in microchannel reactor

SUN Yang^1,3, XIE Tian^1,2,3,4, QUAN Hongdong^2,3, YANG Xiuguo^2,3, LI Hongyan^2,3

1. School of Chemistry and Chemical Engineering, Guizhou University, Guiyang 550003, China;
2. Chifeng Ruiyang Chemical Co., Ltd., Chifeng, Inner Mongolia 024076, China;
3. Key Laboratory of Polyol Chemical New Materials Enterprises of Inner Mongolia Autonomous Region, Chifeng, Inner Mongolia 024076, China;
4. National Key Laboratory for Efficient and Comprehensive Utilization of Medium and Low Grade Phosphate Rock and Its Associated Resources, Guiyang 550016, China

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Abstract There are some problems such as low yield of pentaerythritol in domestic industrial production. Using formaldehyde and acetaldehyde as raw materials and sodium hydroxide as catalyst, pentaerythritol was synthesized by microchannel reactor and quantitatively analyzed by liquid chromatography. The effects of reaction temperature, reaction time and raw materials on the yield were investigated. The response surface experiment was designed by Design-Expert 8 software, and the experimental conditions were optimized. The results showed that when the reaction temperature was 44 ℃ and the reaction time was 161 min, n(formaldehyde)∶n(acetaldehyde)=5∶1, the molar yield of pentaerythritol was 93.17%. Compared with the traditional kettle reaction, the molar yield of pentaerythritol is increased by 25.21%, which has the prospect of industrialization.

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	SUN Yang
	XIE Tian
	QUAN Hongdong
	YANG Xiuguo
	LI Hongyan

Keywords： microreactor response surface method pentaerythritol synthesis

Received 2022-03-30;

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SUN Yang, XIE Tian, QUAN Hongdong, YANG Xiuguo, LI Hongyan.Synthesis of pentaerythritol in microchannel reactor[J] Chemcial Industry and Engineering, 2023,V40(6): 70-77

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