Latest Advances of Microbial Production of Succinate
YANG Jian-Gang, ZHU Nian-Qing, CHEN Tao
(Key Laboratory of Systems Bioengineering, Ministry of Education, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China)
Abstract Succinic acid has a huge potential market with wide applications in chemical, food, medicine industry, and so on. Biobased succinate production has attracted much attention in recent years for many reasons such as low price, low pollution or renewable resources. Focusing on the latest achievements in succinate production, this review systematically summarized the focus of the researchers’ attentions nowadays, especially for metabolic engineering and fermentation optimization of Escherichia coli and Corynebacterium glutamicum. At last, guidelines for future studies are also proposed.
2013, Vol. 30 
