化学工业与工程
Home  |   |  About Journal  |  Editorial Board  |  Instruction  |  Subscriptions  |  Download  |  Publication Ethics  |  Contacts Us  |  Chinese
Chemcial Industry and Engineering 2006, Vol. 23 Issue (1) :29-32    DOI:
Article Current Issue | Next Issue | Archive | Adv Search << | >>
Synthesis of 4-[2-(benzoyloxy)ethyl]-3-chloro-1,3-dihydro-2H-indolin-2-one,an Intermidiate of Ropinirole
WANG Jin-gang,WANG Song-qing,ZENG Guo(College of Pharmaceuticals and Biotechnology,Tianjin University,Tianjin 300072,China)
(College of Pharmaceuticals and Biotechnology,Tianjin University,Tianjin 300072,China

Abstract
Reference
Related Articles
Download: PDF (239KB)   HTML 1KB   Export: BibTeX or EndNote (RIS)      Supporting Info
Abstract Isochroman was synthesized from phenyl ethanol by inner molecular Friedel-Crafts alkylation reaction.The intermidiate of Ropinirole 4-[2-(benzoyloxy)ethyl]-3-chloro-1,3-dihydro-2H-indolin-2-one was prepared from isochroman by ring opening,salt formation,hydrolysis,nitrostyrene formation and Royer reaction.The target product was confirmed by the analysis of TLC,()~(1)H-NMR,IR.The total yield is 31.51%.
Service
Email this article
Add to my bookshelf
Add to citation manager
Email Alert
RSS
Articles by authors
Keywords��   
Received 2006-01-15; published 2006-01-15
Cite this article:   
WANG Jin-gang,WANG Song-qing,ZENG Guo.Synthesis of 4-[2-(benzoyloxy)ethyl]-3-chloro-1,3-dihydro-2H-indolin-2-one,an Intermidiate of Ropinirole[J]  Chemcial Industry and Engineering, 2006,V23(1): 29-32
Copyright 2010 by Chemcial Industry and Engineering