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Chemcial Industry and Engineering 2008, Vol. 25 Issue (3) :276-278    DOI:
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Preparation of Labetalol
GUO Da-liang,ZHU Xiao-wei(Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China)
(Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China

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Abstract Labetalol was prepared from salicylic amide by five steps: acetylation,bromosubstitution,amino-degradation,condensation and reduction.This approach was stable and easy to control.
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Received 2008-05-15; published 2008-05-15
Cite this article:   
GUO Da-liang,ZHU Xiao-wei.Preparation of Labetalol[J]  Chemcial Industry and Engineering, 2008,V25(3): 276-278
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