Abstract The saturated vapor pressures of 4-amino-2,2,6,6-tetramethyl-4-piperidine and 2,2,6,6-tetramethyl-4-hydroxypiperidine were predicted by CSGC-PRV equation,and the Antoine equations for the two components were correlated.The activity coefficients of the components in the binary mixture of 4-amino-2,2,6,6-tetramethyl-4-piperidine and 2,2,6,6-tetramethyl-4-hydroxypiperidine were calculatedby COSMO-SAC method.The Vapor-Liquid Equilibrium(VLE) data of the binary system were obtained by bubble point calculation.Based on the calculation results,4-amino-2,2,6,6-tetramethyl-4-piperi-dine was purified by batch distillation from the binary mixture,and the purity of the obtained product was greater than 99.00%.
WU Tian,CUI Xian-bao,YIN Wei-chao,ZHANG Xiao-kai.Purification of 4-Amino-2,2,6,6-Tetramethyl-4-Piperidine by Distillation[J] Chemcial Industry and Engineering, 2010,V27(4): 294-298
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