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Chemcial Industry and Engineering 2017, Vol. 34 Issue (4) :33-38    DOI: 10.13353/j.issn.1004.9533.20151078
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Optimization for the Extraction of Active Ingredients from Tobacco Leaves by RSM
Zhang Lvhong1, Wang Chengzhuo1, Xiao Xiaoming1, Zhao Shimin2, Li Haohao2, Wang Yujie2, Zhang Zhaopeng3, Jiang Bin1
1. School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China;
2. Luoyang Tobacco Company, Luoyang Henan 471100, China;
3. China Tobacco Zhejiang Industrial Co. Ltd, Hangzhou 310008, China

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Abstract 

The extraction of active ingredients from discard tobacco leaves was investigated by solvent extraction. The effect of extraction time, extraction temperature and liquid-solid ratio was studied using the Response Surface Method (RSM) with the Box-Behnken Design (BBD) method. The optimized extraction temperature was 42.54 ℃, extraction time was 6 hours and liquid-solid ratio was 12.31 mL/g. The extraction yield of essential oil was achieved as high as 7.94% under above conditions and nicotine accounted for 32.25%, pinane for 23.14% and vitamin E for 14.11% of the oleoresin.

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Articles by authors
Zhang Lvhong
Wang Chengzhuo
Xiao Xiaoming
Zhao Shimin
Li Haohao
Wang Yujie
Zhang Zhaopeng
Jiang Bin
Keywordsactive ingredients;   Vitamin E;   solvent extraction;   response surface methodology     
Received 2015-05-06;
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Zhang Lvhong, Wang Chengzhuo, Xiao Xiaoming, Zhao Shimin, Li Haohao, Wang Yujie, Zhang Zhaopeng, Jiang Bin.Optimization for the Extraction of Active Ingredients from Tobacco Leaves by RSM[J]  Chemcial Industry and Engineering, 2017,V34(4): 33-38
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