Preparation of Cyclodextrin Modified Molecularly Imprinted Photonic Crystal for Detecting of Norfloxacin

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Abstract

Maleic anhydride modified β-cyclodextrin (β-CD) was introduced into molecularly imprinting as a novel functional monomer and combined with photonic crystal to fabricate a molecularly imprinted photonic polymer (MIPP). Reactive β-CD monomer carrying vinyl carboxylic acid functional groups was firstly synthesized in our work, then the MIPP film with an opal structure was fabricated by filling precursor solution containing template (norfloxacin), functional monomers, crosslinker (N, N'-methylene bisacrylamide), initiator (ammonium persulfate) into the interstitial spaces of polystyrene photonic crystal templates, followed by a thermal polymerization at 55℃. The three-dimensional, highly-ordered and interconnected macroporous array inverse MIPP was obtained after the templates were removed by ultrasounded in xylene. The MIPP film can response norfloxacin within one minute, when the concentration of norfloxacin increased from 10^-9 mol/L to 10^-4 mol/L, the diffraction wavelength of the photonic crystal shifted from 633 nm to 722 nm. However, the NIPP film did not exhibit significant response.

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	Articles by authors
	Zhang Rong
	Liu Xiaoyan
	Yu Liping

Keywords： photonic crystal； molecular imprinting； β-cyclodextrin； norfloxacin

Received 2014-04-08;

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Zhang Rong, Liu Xiaoyan, Yu Liping.Preparation of Cyclodextrin Modified Molecularly Imprinted Photonic Crystal for Detecting of Norfloxacin[J] Chemcial Industry and Engineering, 2016,V33(3): 39-44

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