3-甲基吡啶合成工艺的研究进展

摘要

吡啶碱，包括吡啶和甲基吡啶（如2-甲基吡啶、3-甲基吡啶和4-甲基吡啶等），是一类典型的含氮化合物，常应用于维生素、杀虫剂等方面，尤其是3-甲基吡啶。综述了3-甲基吡啶合成工艺的研究现状，对其优缺点进行分析，归纳催化剂失活的原因以及再生方法的研究状况。最后，提出甘油/氨为反应原料是合成3-甲基吡啶的理想路线，具有绿色环保、来源可再生和成本低等优点，必将成为未来的发展趋势，展望该工艺今后重点研究方向是开发高性能的催化剂。

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	罗才武
	蒋复量
	李向阳
	张俊
	晁自胜

关键词：吡啶； 3-甲基吡啶；甘油； ZSM-5；催化剂

Abstract：

Pyridine bases, including pyridine and picolines (e.g., 2-picoline, 3-picoline and 4-picoline), are typical N-heterocyclic compounds, which are applied widely in various fields such as vitamin B and pesticide, particularly 3-picoline. In this paper, the current synthesis processes of 3-picoline are reviewed, the related advantages and disadvantages from these pathways are analyzed. The reasons for the deactivation of catalysts are explained and the new regeneration process is introduced. It is concluded that glycerol/ammonia is an ideal pathway for the synthesis of 3-picoline, as it possesses many advantages, e.g., enviroment friendly, safety, sustainable and low cost, which will become the growing trend in the future work. The development of a high-performance catalyst is highly desirable.

Keywords： pyridine； 3-picoline； glycerol； ZSM-5； catalyst

Received 2016-12-08;

Fund:

国家自然科学基金面上项目资助（B21376068）；南华大学博士科研启动基金（2016XQD36）；湖南省教育厅科学研究项目（17C1361）。

Corresponding Authors: 晁自胜,E-mail:zschao@yahoo.com Email: zschao@yahoo.com

About author: 罗才武(1983-),男,博士,现从事纳米材料的制备及其应用。

引用本文:

罗才武, 蒋复量, 李向阳, 张俊, 晁自胜.3-甲基吡啶合成工艺的研究进展[J]. 化学工业与工程, 2018,35(4): 24-31

Luo Caiwu, Jiang Fuliang, Li Xiangyang, Zhang Jun, Chao Zisheng.Advanced Progress in the Synthesis of 3-Picoline[J]. Chemcial Industry and Engineering, 2018,35(4): 24-31

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