A Review of The Main Synthetic Processes of p-Aminobenzotrifluoride

化学工业与工程

Chemcial Industry and Engineering

2001, Vol. 18

Issue (3) :161-166 DOI:

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A Review of The Main Synthetic Processes of p-Aminobenzotrifluoride

CHU Ji\|cheng, LI Wei, LIU Dong\|zhi, ZHAO Hong\|xia, JIANG Jong\|ping (School of Chemical Engineering, Tianjin University, Tianjin 300072,China)

(School of Chemical Engineering, Tianjin University, Tianjin 300072,China

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Abstract p aminobenzotrifluoride is an important intermediate of medicines and agricultural Chemicals, but now is not produced in our country. In the present paper, three main synthetic processes concerning aminolysis of p \|chlorobenzotrifluoride, hydrolysis and exchange fluorination of p \|trihalomethylbenzoisocyanate or p\|tribhalomenthylbenzocarbamylhalide, and trifluoromenthylation of aniline are discussed in detail. Their reaction mechanism are investigated and their advantages and disadvantages are also compared.

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Received 2001-05-15; published 2001-05-15

Cite this article:

CHU Ji\|cheng, LI Wei, LIU Dong\|zhi, ZHAO Hong\|xia, JIANG Jong\|ping .A Review of The Main Synthetic Processes of p-Aminobenzotrifluoride[J] Chemcial Industry and Engineering, 2001,V18(3): 161-166

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