Progress in Synthesis of Peptide Liquid-Phase Segments Ligation

化学工业与工程

Chemcial Industry and Engineering

2006, Vol. 23

Issue (3) :254-259 DOI:

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Progress in Synthesis of Peptide Liquid-Phase Segments Ligation

ZHANG Hong-peng,GAN Yi-ru(School of Chemical Engineering and Technology,Tianjin University,Tianjin 300072,China)

(School of Chemical Engineering and Technology,Tianjin University,Tianjin 300072,China

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Abstract In this paper,peptide segments liquid-phase synthesis technology are introduced and all of these are vivid in protein field recent year.Native chemical ligation,chemo-and regio-selective ligation,Staudinger ligation etc are introduced in detail,their merits and demerits are pointed out by comparing the above technology.Some possible ways to overcome are proposed.The potential technical developments are also discussed.

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Received 2006-05-15; published 2006-05-15

Cite this article:

ZHANG Hong-peng,GAN Yi-ru.Progress in Synthesis of Peptide Liquid-Phase Segments Ligation[J] Chemcial Industry and Engineering, 2006,V23(3): 254-259

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