Research on computational fluid dynamics for simulation of crystallization

Abstract The crystallization process is an important process in many industrial and scientific applications. However, there are complex mass transfer, heat transfer, and fluid dynamics problems in crystallization process. It’s difficult for traditional experimental methods to grasp all the details of the crystallization process, which directly affects the performance and quality of products. Crystallization process simulation based on computational fluid dynamics (CFD) can be used to predict and analyze crystallization process and crystal product quality. Moreover, some quantitative models of crystallization kinetics can be also used in the crystallization process design, crystallization method development, scale-up of crystallizer and other fields. Thus, this article focuses on several numerical solutions of particle balance equations, and provides a detailed introduction of CFD-PBE simulation. The practical applications of this couple solving method in anti-solvent crystallization process, reactive crystallization process and crystallizer design process were also discussed. Finally, the research trends and development directions of CFD-PBE in industrial crystallization are prospected.

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	Articles by authors
	GAO Yuan
	HUA Yuxiang
	ZHANG Jing

Keywords： computational fluid dynamics population balance equations anti-solvent crystallization reactive crystallization scale-up

Received 2023-06-26;

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GAO Yuan, HUA Yuxiang, ZHANG Jing.Research on computational fluid dynamics for simulation of crystallization[J] Chemcial Industry and Engineering, 2024,V41(6): 176-186

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