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��ѧ��ҵ�빤�� 2003, Vol. 20 Issue (6) :443-446    DOI:
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Lipase-Catalyzed Synthesis of L-Ascorbyl Palmitate in Non-aqueous Phase
LIU Chang-bo, GAO Rui-chang(School of Chemical Engineering, Tianjin University,Tianjin 300072, China)
(School of Chemical Engineering, Tianjin University,Tianjin 300072, China

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Abstract�� Lipase-catalyzed synthesis of L-ascorbyl palmitate in non-aqueous phase was studied in this paper.The appropriate lipase and non-aqueous medium were obtained,and several factors which effect the reaction were studied.The results show that the optimum reaction conditions are:the Lipase of Novozyme 435 and tert-butyl alcohol are the optimum pair,the molar ratio of palmitic acid/Vc is 3/1,the reaction temperature is 59��,the reaction time is about 50h,the content of Novozyme 435 is 10g��L~(-1),and the purity of L-AP is up to 95% after purified.
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Received 2003-11-15; published 2003-11-15
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������,������.��ˮ��ø�߻��ϳ�L-����Ѫ���������[J].  ��ѧ��ҵ�빤��, 2003,20(6): 443-446
LIU Chang-bo, GAO Rui-chang.Lipase-Catalyzed Synthesis of L-Ascorbyl Palmitate in Non-aqueous Phase[J].  Chemcial Industry and Engineering, 2003,20(6): 443-446
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