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Chemcial Industry and Engineering 2000, Vol. 17 Issue (3) :125-130    DOI:
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Study on Model Used in the Chromatography Process of Taxol and Cephalmonnine(Ⅰ)
YANG Jun,LIU Bin,YUAN Ying jin (School of Chemical Engineering,Tianjin University,Tianjin 300072,China)
(School of Chemical Engineering,Tianjin University,Tianjin 300072,China

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Abstract The general rate model considering axial dispersion,film mass transfer and effective diffusion in particle was adopted to study the chromatography process of taxol and cephalmonnine.The finite element and orthogonal collocation method was used to transfer these equations to ordinary differential equations and to solve them.The comparison between theory and experiment showed that the model could be agreement with the experimental data very well.In addition,the experiment also showed that axial dispersion is not the main factor affecting the chromatography separation of taxol and cephalmonnine.This made the operation could be done under high linear velocity of flow phase.
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Received 2000-05-15; published 2000-05-15
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YANG Jun,LIU Bin,YUAN Ying jin .Study on Model Used in the Chromatography Process of Taxol and Cephalmonnine(Ⅰ)[J]  Chemcial Industry and Engineering, 2000,V17(3): 125-130
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