Abstract In this paper,the crystallization thermodynamic data,solubility and metastable zone width of 6-aminopenicillanic acid(6APA) were measured by using laser method.The solubility of 6APA was measured under the different temperatures,pH levels,mixed solvents,ionic strength and impurities.The data of metastable zone width of 6APA in aqueous solutions were obtained under the conditions of acid addition rates,initial concentrations of 6APA,temperatures and seed loading.The fundamental data would be key data for industrial design of 6APA production.����
GONG Jun-bo,WANG Jing-kang��.Study on the Property of Crystallization Thermodynamics for 6-Aminopenicillanic Acid[J] Chemcial Industry and Engineering, 2004,V21(1): 33-37
2004, Vol. 21 
