Abstract Solubilities of penicillin G potassium in the mixtures of n-butyl acetate with water ranging from 0.6 to 9.0 mL in 100 mL solvents were measured at 23.5 ��,46.7 �� and 52.0 ��.In several individual mixtures of n-butyl acetate with water,acetic acid or ethanol,solubilities of penicillin G potassium or sodium were determined at 27.0��50.0 ��.The results could be used in the crystallization procedure of penicillin G potassium or penicillin G sodium.
WEI Dong-wei, JIANG Hao-xi, LI Fu-sheng, JIN Ke-xin .Solubilities of Penicillin G Potassium and Penicillin G Sodium in Mixtures Containing n-Butyl Acetate[J] Chemcial Industry and Engineering, 2004,V21(4): 287-289