Advances in Recombinant Protein Drugs Produced in Yeast by Gene Engineering

化学工业与工程

Chemcial Industry and Engineering

2005, Vol. 22

Issue (5) :381-385 DOI:

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Advances in Recombinant Protein Drugs Produced in Yeast by Gene Engineering

XU Ying-qian1, GAN Yi-ru2, HUANG He2(1.School of Chemical Engineering, Anshan University of Science & Technology, Liaoning Anshan 114000, China; 2.School of Chemical Engineering, Tianjin University, Tianjin 300072, China)

(1.School of Chemical Engineering, Anshan University of Science & Technology, Liaoning Anshan 114000, China; 2.School of Chemical Engineering, Tianjin University, Tianjin 300072, China

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Abstract This paper reviews the recent advances in yeast expression systems used in recombinant protein drugs produced by gene engineering,such as the selection of yeast vector system and yeast expression strain, construction of multi-copy strain, the high yeast cell density culture, the recent situation of yeast system applied in expression gene,defect of yeast expression system and countermeasure,etc.

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Received 2005-09-15; published 2005-09-15

Cite this article:

XU Ying-qian1, GAN Yi-ru2, HUANG He2.Advances in Recombinant Protein Drugs Produced in Yeast by Gene Engineering[J] Chemcial Industry and Engineering, 2005,V22(5): 381-385

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