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Chemcial Industry and Engineering 2006, Vol. 23 Issue (2) :98-101    DOI:
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Synthesis of β-DDB Derivatives
ZHAO Lian-juan,WANG Lei,CHANG Jun-biao(College of Pharmaceuticals and Biotechnology,Tianjin University,Tianjin 300072,China)
(College of Pharmaceuticals and Biotechnology,Tianjin University,Tianjin 300072,China

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Abstract Seven new β-DDB derivatives were prepared from gallic acid in 9 steps such as Ullmann coupling reaction,alkylation,benzoylation etc.The structures of these compounds were identified by(()~1HNMR.) This is a new route to the synthesis of β-DDB.A series of β-DDB derivatives with different water-solubility and fat-solubility can be synthesized by reacting with the intermediate for the purpose of finding new antihepatotoxic and anticancer drugs.
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Received 2006-03-15; published 2006-03-15
Cite this article:   
ZHAO Lian-juan,WANG Lei,CHANG Jun-biao.Synthesis of β-DDB Derivatives[J]  Chemcial Industry and Engineering, 2006,V23(2): 98-101
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