Progress in Synthesis and Functionalization of 7-Substituted Indole Catalyzed by Palladium

Abstract 7-substituted indole is key intermediates for forming synthetic drugs and fine chemicals.In this paper,the progresses in preparation methods of 7-substituted indole through palladium-catalyzed reactions in recent 15 years were reviewed.These methods are divided into two categories: the direct synthesis from substituted benzenoid derivatives and the functionalization of performed indoles ring,both of which are introduced in detail in the aspects of mechanism and the processes of reactions.

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Received 2007-09-15; published 2007-09-15

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BI Wei-jia,LI Xiao-jun,ZHANG Guo-liang,ZHANG Feng-bao.Progress in Synthesis and Functionalization of 7-Substituted Indole Catalyzed by Palladium[J] Chemcial Industry and Engineering, 2007,V24(5): 446-452

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