Abstract In this paper,2-fluorin-5-nitroaniline was prepared by reduction of 2,4-dinitrofluorin benzene catalyzed by zinc powder in the mixed solvent of ethanol/water.The optimum conditions were as follows: when mol ratio of 2,4-dinitrofluorin benzene to zinc power was 1��4,mol ratio of ethanol to water in the mixed solvent was 3��2 under refluxing at 50��(60 ��),the yield reached 70.1%.