A Synthetic Process of Benzoprogesterone

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Abstract This paper developed a novel synthesis process of benzoprogesterone. The target compound benzoprogesterone was prepared from 16α,17a-epoxyprogesterone by reduction, oxidation, cyclization and refining. The structure was confirmed by MS and ¹H-NMR. The purity by HPLC was 99.5%, and the total yield rate was 75%, and the novel synthetic process is simple, safe and suitable for industrial production.

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	Wang Yuewei

Keywords： benzoprogesterone； 16α, 17α-epoxyprogesterone； industrial production

Received 2019-03-04;

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Wang Yuewei.A Synthetic Process of Benzoprogesterone[J] Chemcial Industry and Engineering, 2020,V37(2): 38-42

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