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Chemcial Industry and Engineering 2012, Vol. 29 Issue (2) :24-27    DOI:
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Optimizing SFE-CO 2 Extraction of Jingwanhong by Uniform Design
AI  Qing-Bo1, ZHAO  Yu2, GUO  Da-Liang1, HUANG  Qiu-Xia1, PAN  Chao1, LIU  Yu-Xuan1
1Tianjin University of Traditional Chinese Medicine; 
2Tianjin Darentang Jingwanhong Pharmaceutical Co. Ltd.

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Abstract U * 12 (12×6×6) uniform design was chosen to investigate effects of pressure, temperature, entrainment agents ethanol concentration and to obtain the best parameters of supercritical fluid extraction of Jingwanhong . Optimum process parameters were determined by multivariate analysis according to the extraction ratio and contents of  β, β-dimethylacrylalkannin and isomperatorin. Then stepwise regression analysis was performed to obtain the optimum extraction condition: the temperature was 55 ℃, the pressure was 25 MPa, the ethanol concentration was 95%.
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Articles by authors
AI Qing-Bo-1
ZHAO Yu-2
GUO Da-Liang-1
HUANG Qiu-Xia-1
PAN Chao-1
LIU Yu-Xuan-1
Keywords： Jingwanhong   uniform design   SFE-CO2 extraction     
Received 2011-10-14;
Fund:

科技人员服务企业行动资助项目(2009GJA10033)。
Corresponding Authors: 国大亮     Email: silenthawk@163.com
About author: 艾庆波(1986-)，男，硕士研究生，主要从事中药制药工程方面的研究。
Cite this article:   
AI Qing-Bo1, ZHAO Yu2, GUO Da-Liang1, HUANG Qiu-Xia1, PAN Chao1, LIU Yu-Xuan1.Optimizing SFE-CO 2 Extraction of Jingwanhong by Uniform Design[J]  Chemcial Industry and Engineering, 2012,V29(2): 24-27
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