Abstract Cell suspension cultures of lithospermum erythrorhizon produce a large quantity of shikonin derivatives (red naphthoquinone pigments) and a part of them are se creted into the medium. Because of the large volume of liquid medium and the lowconcentration of product in it, pigments recovery from medium becomes one of thekey problems in industrializing this technology. In this paper,three isolation methods──extraction, precipitation and adsorption were used to recover pigments from medium.It resulted that in comparision with extraction, the tradrtional method, precipitation and adsorption simplified the downstream proccess,increased the recovery and accordingly the production cost was cut down greatly. |
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