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化学工业与工程
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��ѧ��ҵ�빤�� 2001, Vol. 18 Issue (6) :395-400    DOI:
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Development of �� -Lactamase Inhibitors
BAI Guo-yi 1,MA Gui-qiu,HOU Man-ling 1,LI Yang 1,CAO Lin 1,WANG Feng-lei 2 (1.School of Chemical Engineering,Tianjin University,Tianjin, 300072,China; 2.Zhejiang Hailisheng Pharmaceutical Group,Zhejiang Zhoushan, 316100,China)
(1.School of Chemical Engineering,Tianjin University,Tianjin, 300072,China; 2.Zhejiang Hailisheng Pharmaceutical Group,Zhejiang Zhoushan, 316100,China

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Abstract�� The uses and mechanism of ��-lactamase inhibitors were introduced. Three kinds of most widely used inhibitors-clavulanic acid,sulbactam and tazobactam were emphatically described,including their raw materials\,synthesis routine and so on. Their inhibitory activities were also compared here.
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Received 2001-11-15; published 2001-11-15
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�׹���,�����,������,����,����,������.��-������ø���Ƽ����о���չ[J].  ��ѧ��ҵ�빤��, 2001,18(6): 395-400
BAI Guo-yi 1,MA Gui-qiu,HOU Man-ling 1,LI Yang 1,CAO Lin 1,WANG Feng-lei 2 .Development of �� -Lactamase Inhibitors[J].  Chemcial Industry and Engineering, 2001,18(6): 395-400
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