BAI Guo-yi 1,MA Gui-qiu,HOU Man-ling 1,LI Yang 1,CAO Lin 1,WANG Feng-lei 2 (1.School of Chemical Engineering,Tianjin University,Tianjin, 300072,China; 2.Zhejiang Hailisheng Pharmaceutical Group,Zhejiang Zhoushan, 316100,China)
(1.School of Chemical Engineering,Tianjin University,Tianjin, 300072,China; 2.Zhejiang Hailisheng Pharmaceutical Group,Zhejiang Zhoushan, 316100,China
Abstract��
The uses and mechanism of ��-lactamase inhibitors were introduced. Three kinds of most widely used inhibitors-clavulanic acid,sulbactam and tazobactam were emphatically described,including their raw materials\,synthesis routine and so on. Their inhibitory activities were also compared here.
BAI Guo-yi 1,MA Gui-qiu,HOU Man-ling 1,LI Yang 1,CAO Lin 1,WANG Feng-lei 2 .Development of �� -Lactamase Inhibitors[J]. Chemcial Industry and Engineering, 2001,18(6): 395-400