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�ؼ���� ׺�ȡ��ⷴӦ 4-�� ϳ� ��ɫ��ѧ

Abstract�� The nucleophilic aromatic substitution for hydrogen reaction is an environmentally benign organic synthesis reaction.4-aminodiphenylamine is an important industrial intermediate.In its synthesis process the pollution is very serious.Flexsys company applied the nucleophilic aromatic substitution for hydrogen reaction to the synthesis of 4-aminodiphenylamine and solved the pollution problem.For this contribution,they were awarded the 1998 Presidential Green Chemistry Challenge Prize.The traditional synthesis methods of 4-aminodiphenylamine,the mechanism of nucleophilic aromatic substitution for hydrogen reaction and the application of nucleophilic aromatic substitution for hydrogen in the synthesis of 4-aminodiphenylamine were reviewed.��

Keywords��

Received 2003-09-15; published 2003-09-15

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��ڷ�,��Ȩ.��׺�ȡ��ⷴӦ��4-��ĺϳ�[J]. ��ѧ��ҵ�빤��, 2003,20(5): 297-302

LIU Teng-fei, WANG Ya-quan��al Engineering,��Tianjin University, Tianjin 300072, China)��.The Nucleophilic Aromatic Substitution for Hydrogen and Its Application in the Synthesis of 4-Aminodiphenylamine[J]. Chemcial Industry and Engineering, 2003,20(5): 297-302

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