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化学工业与工程
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��ѧ��ҵ�빤�� 2003, Vol. 20 Issue (6) :347-350    DOI:
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Synthesis of Morpholine Derivatives
XING Peng,WANG Yong,CHEN Li-gong(School of Pharmaceutical Science & Technology,Tianjin University,Tianjin 300072,China)
(School of Pharmaceutical Science & Technology,Tianjin University,Tianjin 300072,China

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Abstract�� The synthesis of morpholine derivatives was investigated in this paper,particularly,synthetic technology of N-methylmorpholine from morpholine,formaldehyde and formic acid,N-methylmorpholine was isolated in the yield of 92%.The technology for production of N-methylmorpholine oxide was established in this paper.Synthesis of moclobimide and N-(2-aminoethyl) morpholine,an intermidiate of moclobimide,was also examined.
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Received 2003-11-15; published 2003-11-15
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����,����,������.����������ĺϳ��о�[J].  ��ѧ��ҵ�빤��, 2003,20(6): 347-350
XING Peng,WANG Yong,CHEN Li-gong.Synthesis of Morpholine Derivatives[J].  Chemcial Industry and Engineering, 2003,20(6): 347-350
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