手性4-哌啶酮衍生物的合成

摘要哌啶酮及其衍生物是一类非常重要的医药、农药和化工中间体。采用手性羟胺类化合物(手性试剂)与丙烯酸甲酯反应成功地合成了几个新的含羟基的手性N取代4-哌啶酮类化合物,采用核磁共振波谱对其结构进行了表征。

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	孙居锋
	陈立功

关键词：哌啶酮手性试剂羟胺手性化合物

Abstract： Piperidones and its derivatives are a class of compounds with pharmaceutical and agricultural importance.Several new chiral compounds of N-substituted 4-piperidones were obtained from chiral reagent hydroxylamines and methyl acrylate.Their structures were proved by()~1H NMR and()~(13)C NMR.

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Received 2006-09-15; published 2006-09-15

引用本文:

孙居锋;陈立功;.手性4-哌啶酮衍生物的合成[J]. 化学工业与工程, 2006,23(5): 396-399

SUN Ju-feng,CHEN Li-gong.Synthesis of Chiral 4-Piperidones[J]. Chemcial Industry and Engineering, 2006,23(5): 396-399

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