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化学工业与工程
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��ѧ��ҵ�빤�� 2008, Vol. 25 Issue (3) :276-278    DOI:
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Preparation of Labetalol
GUO Da-liang,ZHU Xiao-wei(Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China)
(Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China
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Abstract�� Labetalol was prepared from salicylic amide by five steps: acetylation,bromosubstitution,amino-degradation,condensation and reduction.This approach was stable and easy to control.
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Received 2008-05-15; published 2008-05-15
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������;����ޱ;.��������ĺϳ�[J].  ��ѧ��ҵ�빤��, 2008,25(3): 276-278
GUO Da-liang,ZHU Xiao-wei.Preparation of Labetalol[J].  Chemcial Industry and Engineering, 2008,25(3): 276-278
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