Abstract:
5-aminobenzimidazolone was prepared from 5-nitrobenzimidazolone by hydrazine hydrate reduction. This method is mild, safe and environmentally friendly. The effect of solvents on the preparation of 5-acetylacetamidobenzimidazolone was studied. When ethyl acetate was used as solvent in this reaction, 5-acetylacetamidobenzimidazolone was synthesized by the reaction of 5-amino benzimidazolone with diketene, the yield was 89.3%.
ZHANG Zhen-Yu, ZHANG Jing, SHEN Hai-Jiao, MA Jian-Yu, QU Hong-Mei.Synthesis of 5-Acetylacetamidobenzimidazolone[J]. Chemcial Industry and Engineering, 2014,31(1): 24-32