2-�׻��ĺϳ�

ժҪ ��ƺϳ��Ҷ��Ϣ�� 3,7-��׻� -2ʮ��Ŀ�� ,��Ⱥϳ��һ��Ҫ�Ľṹ��Ԫ 2 ��λ��ᡣ�Ա��Ϊԭ�� ,��׻��ˮ�⡢�� ,�ϳ�� 2 -�׻�� ,��Ϊ 2 4 2 %��

	Service

	�ѱ��Ƽ��
	��ҵ��
	��ù��
	Email Alert
	RSS
	��
	�ϵt
	��
	��շ�
	��ܿ

�ؼ���� Ϣ�� 2-�׻��

Abstract�� In the study on the synthesis of sex pheromone of pine saw fly, the 2-Methyl octanoic acid, an important synthon block of the sex pheromone was synthesiszed in this paper. It was obtained from diethyl malonate in about 24 2% yield through hexylation, methylation, hydrolysis and decarboxylation.

Keywords��

Received 2001-09-15; published 2001-09-15

��ñ��:

�ϵt,��,��շ�,��ܿ.2-�׻��ĺϳ�[J]. ��ѧ��ҵ�빤��, 2001,18(5): 303-307

MENG Yi, CHEN Li-gong, GU Xian-feng, SONG Yun .Synthesis of 2-Methyl Octanoic Acid[J]. Chemcial Industry and Engineering, 2001,18(5): 303-307

[1]	BERGSTROMG ,WASSGRENAB ,ANDER BRANTO ,etal.Sexpheromoneofthepinesaw flydiprionpini(hymenoptera diprionidae):chemi calidentification,synthesisandbiologicalactivity[J].Experientia.1995,51:370-380
[2]	BYSTROMS ,HOGBERGHE ,NORINT .Chiralsynthesisof(2S ,3S ,7S)-3,7-dimethylpenta decan-2-acetateandpropionate,potentialsexpheromonecompoundsofthepinesawfly[J].Tetrahedron.1981,37:2249-2254
[3]	MaYERSAI ,KNAUSG ,KAMATAK ,etal.AsymmetricsynthesisofRandS��-alkyalkanoicacidsfrommetalationandalkylationofchiral2-oxazolines[J].JAmChemSoc,1976,98(2):567-576.
[4]	EVANSDA ,ENNISMD ,MATHERDJ .Asymmetricalkylationreactionofchiralimideeno lates.Apracticalapproachtotheenantioselectivesynthesisof�� substitutedcarboxylicacidderiva tives[J].JAmChemSoc,1982,104:1737-1739.
[5]	LINGQ ,HJALMARSSONM ,HOGBERGHE ,etal.Asymmetricsynthesisof2-alkylalkanoicacidsviaalkylationofchiralamideanions[J].ActaChemScandB ,1984,38:795-801.
[6]	MYERSAG ,YANGBH ,CHENH ,etal.Useofpseudoephedrineasapracticalchiralauxiliaryforasymmetricsynthesis[J].JAmChemSoc,1994,116:9361-9362.
[7]	POUCHERTCJ.TheAldrichlibraryofinfraredspectra[M].US :AldrichChemicalCompanyInc,1981.