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Abstract�� Development of drug dosage forms to a great extent depends on the development of drug auxiliary materials.The development of a new type of polymeric drug auxiliary materials will bring on the developing of novel dosage forms technology and new dosage forms of a block of drugs.Therefore,the development of pressure-sensitive adhesives(PSAs) used in drugs is very important for developing of transdermal drug delivery system(TDDS).This article mainly discusses the developing of PSA used in TDDS home and abroad,including the traditional PSAs and the newest development of PSAs.

Keywords��

Received 2002-11-15; published 2002-11-15

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��־��,��,��.��ҩ��͸Ƥ��Ƽ��ѹ��½�չ[J]. ��ѧ��ҵ�빤��, 2002,19(6): 437-441

GONG Zhi-chao,DONG An-jie,DENG Lian-dong .The Novel Development of Pressure-sensitive Adhesives Used in Transdermal Drug Delivery System[J]. Chemcial Industry and Engineering, 2002,19(6): 437-441

[1]	½��.ҩ��¼��¼��[M ].��:��,1998.
[2]	֣��.��Ƥ��ҩ�¼��[M].��:��,1997.
[3]	CHIVERSRA .Easyremovalofpressuresensitiveadhesivesforskinapplications[J].InternationalJournalofAdhesion&Adhesives.2001,21:381-388
[4]	KIMJH ,CHOYJ ,CHIOHK .Effectofvehiclesandpressuresensitiveadhesivesonthepermeationoftacrineacrosshairlessmouseskin[J].IntJPharm,2000,196:105-113.
[5]	ԪӢ��,��,��.��ҩ�ִ��ؼ��[M].��:��,2002.
[6]	CHRISTENSENSF ,MCKINLEYGH .Rheologicalmodelingofthepeelingofpressure-sensitivead hesivesandotherelastomers[J].InternationalJournalofAdhesion&Adhesives.1998,18:333-343
[7]	YAMAMOTOM ,NAKANOF ,DOIT ,etal.Syn thesisandPSAperformancestudyfornovelacrylicandbutylacrylateblockcopolymers[J].Interna tionalJournalofAdhesion&Adhesives.2002,22:37-40
[8]	CHIRIACAP .Theimprovementofadhesivecharacterofanacrylovinylicmacromolecularcom pound[J].PolymerTesting,2001,20:873-877.
[9]	SRINIVASANV ,CHARLESE .Transdermaldrugdeliverymatrixforcoadministeringestradiolandaonthersteroid[P].WO :9803137,1998-07-21.
[10]	BATTPP ,RAULVA .Methodofcontrollingre leaseofanactiveordrugfromasiliconematrix[P].US :5597584,1997-01-27.
[11]	IZAM ,STOIANOVICIG ,VIORAG ,etal.Hydro gelsofpoly(ethyleneglycol):mechanicalcharac terizationandreleaseofamodeldrug[J].JournalofControlledRelease,1998,52:41-51.
[12]	TSUNEMINEN ,TANAKAY ,BANBAA .Water-dispersiontypepressure-sensitiveadhesivecomposition,methodofproductionthereof,andprssure-sensitiveadhesiveproductempolyingthesame[P].US :6121355,2000-09-18.
[13]	�¹��,�Ű,��ı��,��.ˮ�Ծ۰��Ʊ��ܵ��о�[J].��ӽ��,1999,15(2):97-102.
[14]	CHANGTL ,KUOSH ,SHAHK ,etal.Polyure thanepressure-sensitiveadhesives[P].US :5952422,1999-09-14.