Brönsted-Lewis双酸性离子液体催化合成<em>L</em>-丙交酯

摘要

丙交酯是聚乳酸生产过程中重要的中间体。制备不同SnCl₂摩尔分数的Brönsted-Lewis双酸性离子液体（[HSO₃-bmim]Cl-SnCl₂），将其用作通过预聚路径法合成L-丙交酯的催化剂。研究离子液体中SnCl₂含量对催化活性的影响。考察催化剂用量、反应温度和反应时间对粗丙交酯产率的影响。结合反应残渣的表征结果，提出可行的反应残渣和离子液体催化剂的循环利用方案，结果表明：经过3轮的循环利用，催化剂活性基本不变，基于添加的L-乳酸计算的粗丙交酯产率高达90.99%~92.64%。

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	姜斌
	澹台晓伟
	肖晓明
	邓林
	赵秋迪
	李楠楠

关键词： Brönsted-Lewis双酸性离子液体；催化； L-丙交酯；合成；活性；残渣的循环利用

Abstract：

L-Lactide is an important intermediate in the industrial production of PLA. Brönsted-Lewis acid ionic liquids (ILs) [HSO₃-bmim]Cl-SnCl₂with different molar fractions of tin(Ⅱ) chloride were successfully prepared, and applied for the preparation of L-Lactide by the prepolymer route. The effects of different amounts of SnCl₂ on catalytic reactivity were studied. The influences of various reaction parameters, such as the dosage of catalysts, reaction temperature, and reaction time, were investigated. Owing to the reutilization of PLLA residue and ILs catalyst, the reiterative lactide synthesis was realized. The recycled catalyst showed no notable loss of activity for 3 circles. Meanwhile, high-quality L-lactide could be selectively produced in high yield (90.99%~92.64%, based on L-lactic acid replenished).

Keywords： Brönsted-Lewis acid ionic liquids； catalysis； L-Lactide； synthesis； reactivity； recycle of residues

Received 2015-04-12;

Corresponding Authors: 肖晓明,E-mail:xmxiao@tju.edu.cn. Email: xmxiao@tju.edu.cn

About author: 姜斌(1966-),男,研究员,博士生导师,研究方向为化工技术开发及设计.

引用本文:

姜斌, 澹台晓伟, 肖晓明, 邓林, 赵秋迪, 李楠楠.Brönsted-Lewis双酸性离子液体催化合成L-丙交酯[J]. 化学工业与工程, 2017,34(5): 55-60

Jiang Bin, Tantai Xiaowei, Xiao Xiaoming, Deng lin, Zhao Qiudi, Li Nannan.Synthesis of L-Lactide Catalyzed by Brönsted-Lewis Acidic Ionic Liquids[J]. Chemcial Industry and Engineering, 2017,34(5): 55-60

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