Abstract��
The extraction process of flavonoids from Frutus aurantii immaturus using pressurized extraction(PE) was studied and compared with reflux extraction.Parameters affecting PE procedure such as the concentration of ethanol,solid-liquid ratio,temperature,pressure,time,and material size were discussed and optimized by orthogonal test.The results show that the optimized conditions are as follows: the extraction solvent is 40%(v /v)ethanol aqueous solution,the material size is 60 mesh,ratio of mass of raw material to volume of extraction solvent is 1�� 20,extraction temperature is 130 ��,extraction for 20 min under pressure of 500 kPa.The recovery of extraction could reach 4.16 �� with the extraction rate of 2.08 mg /(g·min).With reflux extraction under the same solid-liquid ratio of extraction solvent,the recovery of extraction is 3.44% with the extraction rate of 0.19 mg /(g·min).PE can obviously increase the recovery of extraction.
ZHU Qing-Shu, ZHAO Wen-Ying, JIN Qing, ZHANG Dan-Dan, WEN You-Ying.Extraction of Total Flavonoids from Frutus aurantii immaturus by Pressurized Liquid Extraction[J]. Chemcial Industry and Engineering, 2010,27(5): 415-419
JIANG Y,LI P,LI S,et al.Optimization of pressurized liqiud extraction of five major flovanoids from Lysimachia clethroide[J].Journal of Pharmaceutical and Biomedical Analysis.2007,43:341-345
2010, Vol. 27 
